Infection
Studies on the time of infection

As part of a study conducted in 12 German pig production operations (M. hyo positive, no M. hyo vaccination), blood samples were examined for antibodies . The following graph sums up the results from all 12 operations. The frequency of animals with positive antibody results - i.e. animals that were already infected with M. hyo - is shown for the different age groups as a bar. The line indicates the schematic course of antibody-positive piglets/growers/finisher pigs.

Following the decrease in maternal antibodies, production of infection-induced antibodies only rises after 12 weeks of age.  
* The mean antibody level in the colostrum of the sows was taken as representative value of the antibody level in the blood of the neonatal piglets (P).

 

The study revealed that three weeks after birth, in general only a low level of passive immunity from maternal antibodies remained and that unvaccinated animals in the M. hyo-positive herds contracted the infection relatively late. The increase in number of antibody-positive animals after 12 weeks of age indicates that an infection occurred at the earliest at the age of eight to nine weeks. These test results concur with those of a series of other current studies.
Recent scientific tests confirming a late time of infection with M. hyo
  Number of examined herds Age in weeks at seroconversion (first presence of antibodies)
E. große Beilage, 1999

4

19 - 22 WOA
M. Kobisch, 2001

3

about 18 WOA
M. Andreasen, 2001

9

18 WOA (1 herd)
19 WOA (4 herds)
20. WOA (2 herds)
21. WOA (2 herds)
V. Ohlinger, 2000

12

From 12 WOA  (3 herds)
From 16 WOA  (6 herds)
From 24 WOA  (3 herds)
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Transmission

The pathogen can be introduced from outside the herd or can be transmitted within the herd. Studies have demonstrated that infection with M. hyo does not generally occur before nine weeks of age.

External transmission

Internal Transmission

Time of infection
Studies on the time of infection